Secretory endometrium dating

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The maturation process of the endometrium is mediated by ovarian sex steroid hormones.In clinical practice, morphological information on endometrial maturation is available from histological evaluation and ultrasound assessment.

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In this context, it was felt to be of interest whether or not the hysteroscopic appearance of the endometrium is associated with early pregnancy loss as well as with implantation failure of fertilized ovum.When accurately performed, endometrial dating provides valuable information.A total of 172 patients who underwent hysteroscopic assessment of the endometrium and then became pregnant, was analysed retrospectively to explore the relationship between endoscopic findings and early phase pregnancy outcome after implantation.Histological examination of the endometrium and assay of serum progesterone and oestrogen were carried out simultaneously with hysteroscopy. Of the remaining 160 patients, 62 (38.8%) were classified endoscopically as having `good' mid-secretory endometrium and 98 (61.3%) as `poor', between one and four cycles prior to the conception cycle.There were no clinical differences between these two groups, except that the frequency of patients with a history of early abortion was significantly higher in the `poor' group (25.5%) than in the `good' group (8.1%) ( 0.05).

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